实验室杨雪等同学在Journal of Magnetic Resonance期刊上发表了题为《Multiple-targeting NMR Signal Selection by Optimal Control of Nuclear Spin Singlet》的文章,通讯作者为姚叶锋老师和魏达秀老师,发表日期为2022年3月4号。(https://doi.org/10.1016/j.jmr.2022.107188)
Selectively probing specific molecules in complex mixtures with nuclear magnetic resonance promises new insights into molecular structures or molecular interaction. Such a study often can be further facilitated when two or more objects in chemical moieties of interest can be precisely targeted. Herein, we proposed a novel method to implement the multiple-targeting signal selection by optimal control of the spin singlets of two or more targeted spin systems from one or more molecules. This method can endow the conventional nuclear magnetic resonance (NMR), magnetic resonance image (MRI) and magnetic resonance spectrum (MRS) with the multiple-targeting signal selectivity to selectively probe several targeted molecules and/or chemical groups simultaneously.